Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905512 | 0.92 | ALDH1A1 (0.36) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8424864 | 0.90 | ALDH1A1 (0.35) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8428655 | 0.90 | ALDH1A1 (0.35) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8906740 | 0.88 | TK1 (0.36) | ALDH1A1NPSR1TK1 | |
| SCHEMBL2056759 | 0.88 | TK1 (0.39) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8424228 | 0.86 | ALDH1A1 (0.35) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8905292 | 0.86 | LMNA (0.35) | ALDH1A1NPSR1TK1 | |
| SCHEMBL10393887 | 0.84 | ALDH1A1 (0.33) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8426572 | 0.84 | ABCG2 (0.35) | ALDH1A1NPSR1TK1 | |
| SCHEMBL6830811 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677439-A | PREVENTION GENE EXPRESSION | SANOFI (FR) | 1997-10-14 | — | — | US | disclosed |
| EP-0541722-B1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING WINTHROP INC (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1992002534-A2 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING DRUG, INC. (US) | 1992-02-20 | — | — | WO | disclosed |