Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609252 | 1.00 | IGF1R (0.65) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL7008253 | 1.00 | IGF1R (0.65) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL9026682 | 0.98 | IGF1R (0.67) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL81497 | 0.92 | IGF1R (0.63) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL9241133 | 0.83 | AHR (0.50) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL908524 | 0.83 | PNMT (0.61) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL15689781 | 0.81 | IGF1R (0.47) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL11332028 | 0.80 | PNMT (0.70) | IGF1RALOX15PNMTTAAR1PYGL | |
| SCHEMBL22333700 | 0.80 | SIGMAR1 (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL11332990 | 0.80 | PNMT (0.70) | IGF1RALOX15PNMTTAAR1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |