Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067104 | 0.92 | CYP2D6 (0.53) | CYP2D6ALDH1A1KDM4EKDM1ACYP1A2 | |
| SCHEMBL19071936 | 0.82 | NOX1 (0.47) | CYP2D6TRPA1CYP1A2CYP2A6MAPT | |
| SCHEMBL8712586 | 0.79 | KDM1A (0.46) | CYP2D6ALDH1A1KDM4EKDM1ACYP1A2 | |
| SCHEMBL8715308 | 0.79 | PTGS1 (0.46) | CYP2D6ALDH1A1KDM4EKDM1ACYP1A2 | |
| SCHEMBL13212473 | 0.78 | MAPT (0.48) | ALDH1A1KDM4EGAAKDM1AMAPT | |
| SCHEMBL17356870 | 0.77 | CYP1A2 (0.45) | CYP2D6KDM4EGAAKDM1ACYP1A2 | |
| SCHEMBL15237156 | 0.77 | DRD2 (0.49) | ALDH1A1KDM1AMAPTHPGDLMNA | |
| SCHEMBL13888145 | 0.75 | MAOA (0.63) | CYP2D6KDM1ACYP1A2MAPTMEN1 | |
| SCHEMBL23265178 | 0.75 | KDM1A (0.43) | CYP2D6ALDH1A1KDM4EKDM1ACYP1A2 | |
| SCHEMBL21765343 | 0.74 | TRPA1 (0.44) | CYP2D6ALDH1A1TRPA1CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787230-A1 | BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT | NOVO NORDISK A/S (DK) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012846-A1 | BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT | NOVO NORDISK A/S (DK) | 1996-05-02 | — | — | WO | disclosed |