Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906566 | 0.95 | TAS2R8 (0.33) | TAS2R8ROCK2 | |
| SCHEMBL8906968 | 0.94 | — | — | |
| SCHEMBL8907061 | 0.84 | AGTR1 (0.38) | TAS2R8BRD4 | |
| SCHEMBL9096116 | 0.81 | AGTR1 (0.39) | — | |
| SCHEMBL8907406 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL8905606 | 0.81 | — | — | |
| SCHEMBL8905232 | 0.80 | — | — | |
| SCHEMBL8906471 | 0.80 | AGTR1 (0.43) | TAS2R8BRD4 | |
| SCHEMBL8905649 | 0.79 | AGT (0.41) | TAS2R8 | |
| SCHEMBL9096342 | 0.78 | PPARG (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |