Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906713 | 0.91 | AGTR1 (0.45) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8905585 | 0.89 | PPARG (0.43) | PPARGEDNRAKDM4EABCC3ABCC4 | |
| SCHEMBL8905974 | 0.86 | PPARG (0.45) | PPARGDHODHKDM4EABCC3ABCC4 | |
| SCHEMBL8906712 | 0.86 | PPARG (0.49) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8905700 | 0.85 | PPARG (0.50) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8906533 | 0.84 | PPARG (0.43) | PPARGDHODHKDM4EABCC3ABCC4 | |
| SCHEMBL8905384 | 0.84 | PPARG (0.46) | PPARGDHODHKDM4EABCC3ABCC4 | |
| SCHEMBL8905690 | 0.84 | PPARG (0.47) | PPARGKDM4EABCC3ABCC4USP2 | |
| SCHEMBL8906316 | 0.83 | PPARG (0.44) | PPARGDHODHKDM4EABCC3ABCC4 | |
| SCHEMBL8906956 | 0.83 | ALDH1A1 (0.44) | PPARGDHODHLMNAKDM4EABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |