Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907296 | 0.83 | MAOA (0.46) | ALDH1A1HPGDNPC1RAB9ALMNA | |
| SCHEMBL17710702 | 0.82 | LMNA (0.45) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL9550392 | 0.80 | ERAP1 (0.35) | ALDH1A1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL3965575 | 0.80 | CRBN (0.48) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL28190109 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL10439641 | 0.78 | MAOA (0.51) | ALDH1A1HPGDNPC1RAB9APOLB | |
| SCHEMBL14396785 | 0.78 | KDM4E (0.43) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL4176810 | 0.78 | PTGER1 (0.44) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL17711004 | 0.78 | LMNA (0.49) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL14397250 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4EHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658587-A | TRANSDERMAL PATCH | FLORA INC. (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1997014419-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1997-04-24 | — | — | WO | disclosed |