Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907162 | 0.92 | ALDH1A1 (0.50) | KMT2AALDH1A1POLBHPGDLMNA | |
| SCHEMBL6475232 | 0.90 | KMT2A (0.40) | KMT2ASIGMAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8906958 | 0.88 | KMT2A (0.47) | KMT2ASIGMAR1AKR1B1ALDH1A1PYGL | |
| SCHEMBL8905949 | 0.86 | KMT2A (0.52) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 | |
| SCHEMBL8906506 | 0.84 | KMT2A (0.50) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 | |
| SCHEMBL8906824 | 0.83 | KMT2A (0.49) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 | |
| SCHEMBL8907213 | 0.82 | KMT2A (0.50) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 | |
| SCHEMBL6474633 | 0.82 | KMT2A (0.40) | KMT2ASIGMAR1ALDH1A1POLBLMNA | |
| SCHEMBL8906884 | 0.82 | SMN1; SMN2 (0.49) | KMT2AALDH1A1POLBHPGDLMNA | |
| SCHEMBL8906049 | 0.81 | KMT2A (0.49) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |