Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906830 | 0.92 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPTRECQLMEN1 | |
| SCHEMBL8907366 | 0.89 | KMT2A (0.46) | KMT2ASIGMAR1AKR1B1NR3C1IDO1 | |
| SCHEMBL8905949 | 0.88 | KMT2A (0.52) | KMT2ASIGMAR1AKR1B1SHMT1SHMT2 | |
| SCHEMBL8906506 | 0.83 | KMT2A (0.50) | KMT2ASIGMAR1AKR1B1SHMT1SHMT2 | |
| SCHEMBL8907116 | 0.82 | KMT2A (0.49) | KMT2ASIGMAR1AKR1B1SHMT1SHMT2 | |
| SCHEMBL8906824 | 0.82 | KMT2A (0.49) | KMT2ASIGMAR1AKR1B1SHMT1SHMT2 | |
| SCHEMBL8907198 | 0.82 | SMN1; SMN2 (0.48) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8906430 | 0.81 | SIGMAR1 (0.49) | SIGMAR1NR3C1IDO1SHMT1SHMT2 | |
| SCHEMBL8905527 | 0.81 | DRD2 (0.42) | ALDH1A1TP53MAPTPYGLDRD2 | |
| SCHEMBL8907390 | 0.80 | ALDH1A1 (0.53) | KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065524-C | Substituted phenyl acetanides, process for their preparation and intermediates thereof | BAYER AG (DE) | 2001-05-09 | — | — | CN | disclosed |
| CN-1044366-C | Aryl pyrrolidine diketone derivative and preparation method thereof, and pesticide and herbicide containing aryl pyrrolidine diketone derivative and pesticide and herbicide application thereof | BAYER AG (DE) | 1999-07-28 | — | — | CN | disclosed |
| CN-1190650-A | Substituted phenyl acetanides, process for their preparation and intermediates thereof | BAYER AG (DE) | 1998-08-19 | — | — | CN | disclosed |
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| CN-1086213-A | Substituted 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives | BAYER AG (DE) | 1994-05-04 | — | — | CN | disclosed |