Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804701 | 0.81 | NPC1 (0.58) | L3MBTL1CHRM2CA2EPHX1GAA | |
| SCHEMBL1521016 | 0.80 | PTPRF (0.57) | TSHRL3MBTL1CHRM2CA2EPHX1 | |
| SCHEMBL27968659 | 0.80 | L3MBTL1 (0.57) | TSHRL3MBTL1CHRM2CA2EPHX1 | |
| SCHEMBL6956941 | 0.79 | KMT2A (0.56) | L3MBTL1CHRM2CA2EPHX1MEN1 | |
| SCHEMBL14861111 | 0.79 | GAA (0.58) | TSHRL3MBTL1CA2EPHX1GAA | |
| SCHEMBL2850347 | 0.79 | APOBEC3A (0.58) | L3MBTL1CA2EPHX1GAAMEN1 | |
| SCHEMBL4496741 | 0.79 | MMP13 (0.59) | L3MBTL1MEN1KMT2AMMP13 | |
| SCHEMBL13609107 | 0.78 | CA2 (0.61) | TSHRL3MBTL1CA2EPHX1GAA | |
| SCHEMBL4587579 | 0.78 | CA2 (0.58) | TSHRL3MBTL1CHRM2CA2EPHX1 | |
| SCHEMBL4587574 | 0.78 | CA2 (0.55) | TSHRL3MBTL1CHRM2CA2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997021666-A1 | ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS | GLAXO GROUP LIMITED (GB) | 1997-06-19 | — | — | WO | disclosed |