Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.42 |
| ▸ | RXRB | P28702 | 4/20 | 0.42 |
| ▸ | RXRG | P48443 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARG | P13631 | 3/20 | 0.41 |
| ▸ | HNF4A | P41235 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207922 | 0.84 | RARB (0.61) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7207926 | 0.84 | RARB (0.61) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8906010 | 0.83 | RXRA (0.49) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8905251 | 0.82 | RXRA (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8904416 | 0.82 | RXRA (0.52) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8907180 | 0.81 | RXRA (0.42) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7999260 | 0.78 | RARB (0.64) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8905100 | 0.77 | RXRA (0.53) | RXRARXRBRXRGRARARARB | |
| SCHEMBL8459590 | 0.74 | RXRA (0.45) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6674718 | 0.74 | RXRA (0.45) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |