Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.49 |
| ▸ | RARA | P10276 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARG | P13631 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905251 | 0.97 | RXRA (0.53) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905607 | 0.87 | RXRA (0.42) | RXRARXRBRXRGTRPA1TRPM2 | |
| SCHEMBL8910622 | 0.84 | RXRA (0.43) | RXRARARARARBRARGRXRB | |
| SCHEMBL8906153 | 0.84 | RXRA (0.45) | RXRARXRBRXRG | |
| SCHEMBL8907175 | 0.83 | RXRA (0.42) | RXRARARARARBRARGRXRB | |
| SCHEMBL8904416 | 0.83 | RXRA (0.52) | RXRARARARARBRARGRXRB | |
| SCHEMBL7213554 | 0.82 | RARB (0.64) | RXRARARARARBRARGRXRB | |
| SCHEMBL7213560 | 0.82 | RARB (0.64) | RXRARARARARBRARGRXRB | |
| SCHEMBL10842696 | 0.81 | RARB (0.63) | RXRARARARARBRARGRXRB | |
| SCHEMBL4669367 | 0.81 | RARB (0.63) | RXRARARARARBRARGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | claimed |
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |