Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654342 | 0.92 | P2RX7 (0.36) | PTGER4P2RX7 | |
| SCHEMBL8906981 | 0.92 | RECQL (0.42) | SIGMAR1P2RX7KMT2AMEN1ALDH1A1 | |
| SCHEMBL6474811 | 0.90 | MEN1 (0.42) | SIGMAR1P2RX7KMT2AMEN1ALDH1A1 | |
| SCHEMBL7132879 | 0.90 | MAPK1 (0.37) | P2RX7KMT2AMEN1RECQL | |
| SCHEMBL27535978 | 0.88 | SMN1; SMN2 (0.39) | SIGMAR1PTGER4KMT2AMEN1ALDH1A1 | |
| SCHEMBL8906080 | 0.87 | SHMT1 (0.48) | SIGMAR1P2RX7KMT2AERCC1ERCC4 | |
| SCHEMBL5492364 | 0.85 | OPRM1 (0.34) | KMT2AMEN1ALDH1A1L3MBTL1SLC6A2 | |
| SCHEMBL5929427 | 0.84 | P2RX7 (0.39) | P2RX7KMT2AMEN1 | |
| SCHEMBL8657268 | 0.84 | P2RX7 (0.41) | P2RX7ALDH1A1 | |
| SCHEMBL8650622 | 0.84 | P2RX7 (0.37) | SIGMAR1PTGER4P2RX7RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |