Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 3/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16266862 | 0.96 | MAPT (0.57) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| SCHEMBL1823472 | 0.88 | DGKA (0.62) | MAPTPRKCAPRKCEPRKCQPRKCD | |
| Isopropyl Myristate SCHEMBL5157367 | 0.87 | LMNA (0.79) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| Isopropyl Palmitate SCHEMBL7802437 | 0.87 | LMNA (0.79) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| SCHEMBL31108940 | 0.85 | MAPT (0.58) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| SCHEMBL30701946 | 0.85 | MAPT (0.58) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| Isopropyl Myristate SCHEMBL10785775 | 0.84 | LMNA (0.70) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| SCHEMBL6662785 | 0.84 | MAPT (0.57) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| SCHEMBL9705575 | 0.84 | MAPT (0.57) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| Isopropyl Myristate SCHEMBL8908510 | 0.82 | LMNA (0.82) | LMNAMAPTMAPK1KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658587-A | TRANSDERMAL PATCH | FLORA INC. (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1997014419-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1997-04-24 | — | — | WO | disclosed |
| EP-0756482-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5503843-A | PATCH HAVING EITHER A LIQUID RESERVOIR OR MONOLITHIC MATRIX CONTAINING A PERMEATION ENHANCER AND 2-PHENYL-3-METHYL-8-(1-(4-(METHOXYPHENYL)PIPERAZIN-1-YL)PROPYLAMINO-4 -CARBONYL-4H-CHROMEN-4-ONE; BENIGN PROSTRATE HYPERPLASIA | FLORA INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1995028932-A1 | TRANSDERMAL DELIVERY OF ALPHA ADRENOCEPTOR BLOCKING AGENTS | FLORA INC. (US) | 1995-11-02 | — | — | WO | disclosed |