SCHEMBL8907337

SCHEMBL8907337

CC1CCCCC1(NC(=O)Cc1c(Cl)cccc1Cl)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
SIGMAR1 Q99720 2/20 0.42
AKR1B1 P15121 1/20 0.40
ALDH1A1 P00352 1/20 0.39
PYGL P06737 1/20 0.38
DRD1 P21728 1/20 0.37
GAA P10253 1/20 0.37
ATM Q13315 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36
MEN1 O00255 2/20 0.36
ACKR3 P25106 1/20 0.36
RAB9A P51151 1/20 0.36
GLA P06280 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RECQL P46063 1/20 0.36
P2RX7 Q99572 1/20 0.36
TRPV1 Q8NER1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8907216 0.92 ALDH1A1 (0.50) KMT2AALDH1A1GAAMEN1RAB9A
SCHEMBL6475239 0.90 KMT2A (0.40) KMT2ASIGMAR1ALDH1A1ATMMEN1
SCHEMBL8907139 0.88 KMT2A (0.47) KMT2ASIGMAR1AKR1B1ALDH1A1GAA
SCHEMBL6483262 0.82 KMT2A (0.40) KMT2AALDH1A1GAAATMMEN1
SCHEMBL8907736 0.82 SMN1; SMN2 (0.49) KMT2AALDH1A1GAAMEN1RAB9A
SCHEMBL8907562 0.81 SIGMAR1 (0.44) KMT2ASIGMAR1P2RX7TRPV1
SCHEMBL8650736 0.80 NPC1 (0.38) KMT2ASIGMAR1TAS1R3TAS1R1RAB9A
SCHEMBL8905461 0.80 GAA (0.36) KMT2AALDH1A1GAATAS1R3TAS1R1
SCHEMBL8657819 0.78 P2RX7 (0.42) KMT2ASIGMAR1P2RX7
SCHEMBL6475230 0.77 MEN1 (0.45) KMT2ASIGMAR1ALDH1A1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677449-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5462913-A Pesticides, insecticides, miticides, herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed