Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908934 | 0.91 | CYP26A1 (0.46) | CYP3A4CYP26A1CYP26B1CA12CA1 | |
| SCHEMBL5084222 | 0.79 | CYP3A4 (0.63) | CYP3A4CYP26A1CYP26B1CA12CA1 | |
| SCHEMBL7714840 | 0.79 | CA12 (0.35) | CA12CA1CA2CA7PDK2 | |
| SCHEMBL8440033 | 0.77 | CA12 (0.41) | CA12CA1CA2CA7PDK2 | |
| SCHEMBL6146889 | 0.75 | RARA (0.38) | CYP3A4CYP26A1CYP26B1LMNANPC1 | |
| SCHEMBL8907362 | 0.74 | CYP3A4 (0.48) | CYP3A4CYP26A1CYP26B1CA12CA1 | |
| SCHEMBL7715267 | 0.72 | CA12 (0.35) | CA12CA1CA2CA7PDK2 | |
| SCHEMBL7714849 | 0.71 | RARB (0.39) | CYP26A1CYP26B1CA12CA1CA2 | |
| SCHEMBL6144565 | 0.70 | CYP26A1 (0.46) | CYP3A4CYP26A1CYP26B1TP53RARA | |
| SCHEMBL7715091 | 0.69 | RARB (0.42) | CYP3A4LMNANPC1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514264-B1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-11-15 | — | — | EP | claimed |
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |