SCHEMBL8907360

SCHEMBL8907360

COc1ccc(COC(=O)[C@H](N)Cc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.56
LAP3 P28838 1/20 0.56
LDHA P00338 1/20 0.54
PPARG P37231 1/20 0.54
PPARA Q07869 1/20 0.54
ATM Q13315 1/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
SLC15A1 P46059 1/20 0.50
ALDH1A1 P00352 1/20 0.50
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50
FABP7 O15540 1/20 0.49
FABP5 Q01469 1/20 0.49
SLC6A4 P31645 1/20 0.49
CTSL P07711 1/20 0.47
CTSS P25774 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270126 1.00 LTA4H (0.56) LTA4HLAP3LDHAPPARGPPARA
SCHEMBL6436841 1.00 LTA4H (0.56) LTA4HLAP3LDHAPPARGPPARA
SCHEMBL8907592 1.00 LTA4H (0.56) LTA4HLAP3LDHAPPARGPPARA
SCHEMBL15634364 1.00 LTA4H (0.56) LTA4HLAP3LDHAPPARGPPARA
SCHEMBL1701896 1.00 LTA4H (0.56) LTA4HLAP3LDHAPPARGPPARA
Hydrochloric Acid SCHEMBL6436839 0.99 LTA4H (0.55) LTA4HLAP3LDHAPPARGPPARA
Hydrochloric Acid SCHEMBL6436832 0.99 LTA4H (0.55) LTA4HLAP3LDHAPPARGPPARA
SCHEMBL8033635 0.96 LTA4H (0.53) LTA4HLAP3LDHAPPARGPPARA
Hydrochloric Acid SCHEMBL8033631 0.95 LTA4H (0.52) LTA4HLAP3LDHAPPARGPPARA
SCHEMBL7360502 0.89 LTA4H (0.50) LTA4HLAP3LDHAPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255202-A1 ANTIMICROBIAL COMPOSITION THE PROCTER & GAMBLE COMPANY 2023-08-17 US disclosed
US-20230255202-A1 ANTIMICROBIAL COMPOSITION THE PROCTER & GAMBLE COMPANY 2023-08-17 US disclosed
EP-4226767-A1 ANTIMICROBIAL COMPOSITION The Procter & Gamble Company (US) 2023-08-16 EP disclosed
US-5672605-A ADMINISTERING TO TREAT AUTOIMMUNE DISORDERS, TRANSPLANT REJECTION ABBOTT LABORATORIES (US) 1997-09-30 US disclosed
US-5583139-A Marcolide immunomodulators ABBOTT LABORATORIES (US) 1996-12-10 US disclosed
EP-0729471-A1 SEMISYNTHETIC ANALOGS OF RAPAMYCIN (MACROLIDES) BEING IMMUNOMODULATORS Abbott Laboratories (US) 1996-09-04 EP disclosed
US-5527907-A IMMUNOSUPPRESSANTS ABBOTT LABORATORIES (US) 1996-06-18 US disclosed
WO-1995014023-A1 SEMISYNTHETIC ANALOGS OF RAPAMYCIN (MACROLIDES) BEING IMMUNOMODULATORS ABBOTT LABORATORIES (US) 1995-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255202-A1 ANTIMICROBIAL COMPOSITION ARG1, CUTA, SLC7A1 LTA4H 2153/4885LAP3 2070/4885LDHA 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.