Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766743 | 0.86 | L3MBTL1 (0.46) | MAPTCA2CA9MMP1NAAA | |
| SCHEMBL4772916 | 0.85 | L3MBTL1 (0.56) | MAPTCA2NAAAL3MBTL1MLYCD | |
| SCHEMBL9601827 | 0.83 | MMP1 (0.44) | MMP1NAAAL3MBTL1MLYCDHDAC3 | |
| SCHEMBL4769427 | 0.81 | PLK1 (0.58) | CA1CA2CA9L3MBTL1HDAC3 | |
| SCHEMBL961840 | 0.81 | MAPT (0.47) | KDM4EMAPTHIF1ACA1CA2 | |
| SCHEMBL8908235 | 0.81 | L3MBTL1 (0.42) | CA2MMP1NAAAL3MBTL1MLYCD | |
| SCHEMBL2480571 | 0.79 | RARB (0.50) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2310994 | 0.78 | KDM4E (0.61) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL6288870 | 0.77 | BDKRB2 (0.44) | MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL8906739 | 0.77 | MMP1 (0.39) | KDM4ECA2MMP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609848-A | Radiohalogenated small molecules for protein labeling | NEORX CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |
| US-5213787-A | RADIOHALOGENATED SMALL MOLECULES FOR PROTEIN LABELING | NEORX CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0203764-B1 | RADIOHALOGENATED SMALL MOLECULES FOR PROTEIN LABELING | NEORX CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| US-5045303-A | Radiohalogenated small molecules for protein labeling | NEORX CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| US-4885153-A | Radiohalogenated for proteins | NEORX CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0203764-A2 | Radiohalogenated small molecules for protein labeling | NEORX CORPORATION (US) | 1986-12-03 | — | — | EP | disclosed |