Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905610 | 0.98 | BRD9 (0.32) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL8906880 | 0.93 | BRD9 (0.33) | PARP1TSHRSMN1; SMN2 | |
| SCHEMBL8905932 | 0.91 | BRD9 (0.34) | PARP1TSHRSMN1; SMN2TNKS | |
| SCHEMBL8907406 | 0.86 | LMNA (0.33) | LMNAMAPK1TP53 | |
| SCHEMBL8906568 | 0.85 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL8905606 | 0.84 | — | — | |
| SCHEMBL8905232 | 0.84 | — | — | |
| SCHEMBL8906496 | 0.83 | HSD17B10 (0.30) | HSD17B10 | |
| SCHEMBL8907048 | 0.82 | AGTR1 (0.42) | ALDH1A1 | |
| SCHEMBL8788274 | 0.81 | AGTR1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |