Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 13/20 | 0.46 |
| ▸ | RARA | P10276 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271838 | 0.86 | CYP26A1 (0.64) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL8907898 | 0.74 | CYP26A1 (0.69) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL8907954 | 0.72 | RARG (0.44) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL5084222 | 0.72 | CYP3A4 (0.63) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL5084218 | 0.71 | CYP26A1 (0.67) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL8909052 | 0.70 | CYP3A4 (0.55) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL8907823 | 0.70 | CYP3A4 (0.60) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL5084224 | 0.70 | CYP26A1 (0.72) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL9270229 | 0.70 | RARG (0.62) | CYP3A4CYP26A1CYP26B1RARGRARA | |
| SCHEMBL9196412 | 0.70 | CYP3A4 (0.62) | CYP3A4CYP26A1CYP26B1RARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |