Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 10/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907526 | 0.77 | CYP3A4 (0.43) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL8909052 | 0.77 | CYP3A4 (0.55) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL8907801 | 0.75 | CYP26A1 (0.45) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL8907955 | 0.74 | RARG (0.42) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL9271838 | 0.73 | CYP26A1 (0.64) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL8907475 | 0.72 | CYP3A4 (0.52) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL8907772 | 0.71 | PARP15 (0.50) | PPARGMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8909342 | 0.70 | CYP3A4 (0.43) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL8907823 | 0.69 | CYP3A4 (0.60) | RARGRARARARBCYP26A1CYP3A4 | |
| SCHEMBL9270229 | 0.69 | RARG (0.62) | RARGRARARARBCYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |