Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15715425 | 0.76 | CA1 (0.36) | CA1CA2 | |
| SCHEMBL14590056 | 0.73 | CA1 (0.41) | CA1CA2 | |
| SCHEMBL677702 | 0.72 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL22199552 | 0.71 | CA1 (0.40) | CA1CA2 | |
| SCHEMBL23097419 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL21553610 | 0.71 | KDM4E (0.30) | — | |
| SCHEMBL24401590 | 0.70 | FAAH (0.38) | — | |
| SCHEMBL678153 | 0.70 | LMNA (0.40) | CA1CA2SMN1; SMN2 | |
| SCHEMBL14167250 | 0.70 | MCL1 (0.33) | — | |
| SCHEMBL16280996 | 0.70 | KDM4E (0.42) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813543-A1 | BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028464-A1 | BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-19 | — | — | WO | disclosed |