Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ME2 | P23368 | 1/20 | 0.32 |
| ▸ | ME1 | P48163 | 1/20 | 0.32 |
| ▸ | ME3 | Q16798 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658184 | 0.82 | TDP1 (0.42) | PSMB8PSMB5CYP4F2CYP4A11 | |
| SCHEMBL318285 | 0.80 | KMT2A (0.36) | KMT2ASMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL4769424 | 0.78 | CYP4F2 (0.59) | CYP4F2CYP4A11 | |
| SCHEMBL8906739 | 0.78 | MMP1 (0.39) | KMT2ASMN1; SMN2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL9752036 | 0.78 | L3MBTL1 (0.43) | KMT2ASMN1; SMN2PSMB8PSMB5CYP4F2 | |
| SCHEMBL10589560 | 0.77 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1HPGDHSD17B10 | |
| SCHEMBL112099 | 0.76 | FAAH (0.41) | KMT2APSMB8PSMB5CYP4F2CYP4A11 | |
| SCHEMBL7453768 | 0.76 | F2RL1 (0.53) | KMT2ASMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18353920 | 0.75 | PSMB8 (0.37) | PSMB8PSMB5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL13920679 | 0.75 | FFAR1 (0.42) | KMT2APSMB8PSMB5CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609848-A | Radiohalogenated small molecules for protein labeling | NEORX CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |
| US-5213787-A | RADIOHALOGENATED SMALL MOLECULES FOR PROTEIN LABELING | NEORX CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0203764-B1 | RADIOHALOGENATED SMALL MOLECULES FOR PROTEIN LABELING | NEORX CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| US-5045303-A | Radiohalogenated small molecules for protein labeling | NEORX CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| US-4885153-A | Radiohalogenated for proteins | NEORX CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0203764-A2 | Radiohalogenated small molecules for protein labeling | NEORX CORPORATION (US) | 1986-12-03 | — | — | EP | disclosed |