Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875781 | 0.86 | ALOX15 (0.48) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL11201373 | 0.82 | SLC22A6 (0.44) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL31469845 | 0.80 | THRB (0.47) | ALDH1A1TSHRTDP1 | |
| SCHEMBL7700789 | 0.80 | ALOX15 (0.44) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL7759802 | 0.80 | ALDH1A1 (0.45) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL5988620 | 0.80 | ALOX15 (0.44) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL1054275 | 0.80 | ALDH1A1 (0.48) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL14700477 | 0.78 | ALOX15 (0.43) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL10982034 | 0.78 | ALOX15 (0.43) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL7166620 | 0.78 | ALDH1A1 (0.52) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616615-A | ANTICONVULSANTS | HOWARD UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |
| US-5468775-A | Anticonvulsants | HOWARD UNIVERSITY (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1993017678-A1 | ENAMINONE ESTERS | HOWARD UNIVERSITY (US) | 1993-09-16 | — | — | WO | disclosed |