Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524556 | 1.00 | CCNB2 (0.32) | CCNB2CDK1CCNB1CCNB3HSD17B1 | |
| SCHEMBL8908351 | 0.85 | CHRNB4 (0.31) | HSD17B1HSD17B2IDH1SLC6A3 | |
| SCHEMBL5104033 | 0.85 | CHRNB4 (0.31) | HSD17B1HSD17B2IDH1SLC6A3 | |
| SCHEMBL9559701 | 0.84 | SLC6A3 (0.30) | SLC6A3 | |
| SCHEMBL5016512 | 0.84 | — | — | |
| SCHEMBL10525261 | 0.84 | — | — | |
| SCHEMBL9559683 | 0.75 | — | — | |
| SCHEMBL8676968 | 0.73 | — | — | |
| SCHEMBL6260570 | 0.73 | — | — | |
| SCHEMBL249200 | 0.73 | HSD17B1 (0.47) | CCNB2CDK1CCNB1CCNB3HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337601-B1 | PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT | SCOTIA HOLDINGS PLC (GB) | 1993-05-05 | — | — | EP | claimed |
| US-4992257-A | Dihydroporphyrins and method of treating tumors | EFAMOL HOLDINGS PLC (GB) | 1991-02-12 | — | — | US | claimed |
| EP-0337601-A1 | Porphyrins and medicaments for cancer treatment | SCOTIA HOLDINGS PLC (GB) | 1989-10-18 | — | — | EP | claimed |
| US-12178907-B2 | Binary lipid bilayer-containing vesicles comprising embedded cytotoxic agents and methods of making and using the same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-12-31 | — | — | US | disclosed |
| US-20220142922-A1 | LIPOSOMAL NANOCONSTRUCTS AND METHODS OF MAKING AND USING THE SAME | THE GENERAL HOSPITAL CORPORATION | 2022-05-12 | — | — | US | disclosed |
| EP-3302436-A1 | LIPOSOMAL NANOCONSTRUCTS AND METHODS OF MAKING AND USING THE SAME | The General Hospital Corporation (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016191556-A1 | LIPOSOMAL NANOCONSTRUCTS AND METHODS OF MAKING AND USING THE SAME | THE GENERAL HOSPITAL CORPORATION (US) | 2016-12-01 | — | — | WO | disclosed |
| WO-2012076631-A1 | SYSTEM AND METHOD FOR INTERSTITIAL PHOTODYNAMIC LIGHT THERAPY IN COMBINATION WITH PHOTOSENSITIZERS | SPECTRACURE AB (SE) | 2012-06-14 | — | — | WO | disclosed |
| EP-0758331-A1 | POLYETHYLENE GLYCOL DERIVATISED DIHYDRO OR TETRAHYDRO PORPHYRINS, THEIR PREPARATION AND THEIR USE AS TUMOUR LOCALISING, PHOTOSENSITISING COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029915-A1 | POLYETHYLENE GLYCOL DERIVATISED DIHYDRO OR TETRAHYDRO PORPHYRINS, THEIR PREPARATION AND THEIR USE AS TUMOUR LOCALISING, PHOTOSENSITISING COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1995-11-09 | — | — | WO | disclosed |
| EP-0337601-B1 | PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT | SCOTIA HOLDINGS PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| US-5162519-A | Porphyrins and cancer treatment | EFAMOL HOLDINGS PLC (GB) | 1992-11-10 | — | — | US | disclosed |
| US-4992257-A | Dihydroporphyrins and method of treating tumors | EFAMOL HOLDINGS PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0337601-A1 | Porphyrins and medicaments for cancer treatment | SCOTIA HOLDINGS PLC (GB) | 1989-10-18 | — | — | EP | disclosed |