⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424888 | 0.82 | — | — | |
| SCHEMBL9559701 | 0.76 | SLC6A3 (0.30) | — | |
| SCHEMBL10524556 | 0.75 | CCNB2 (0.32) | — | |
| SCHEMBL8907704 | 0.75 | CCNB2 (0.32) | — | |
| SCHEMBL498541 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL8676968 | 0.70 | — | — | |
| SCHEMBL6260570 | 0.70 | — | — | |
| SCHEMBL12373844 | 0.69 | — | — | |
| SCHEMBL9404581 | 0.68 | HPGD (0.47) | — | |
| SCHEMBL4048481 | 0.68 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337601-B1 | PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT | SCOTIA HOLDINGS PLC (GB) | 1993-05-05 | — | — | EP | claimed |
| EP-0337601-B1 | PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT | SCOTIA HOLDINGS PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| US-5162519-A | Porphyrins and cancer treatment | EFAMOL HOLDINGS PLC (GB) | 1992-11-10 | — | — | US | disclosed |
| US-4992257-A | Dihydroporphyrins and method of treating tumors | EFAMOL HOLDINGS PLC (GB) | 1991-02-12 | — | — | US | disclosed |