Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14087040 | 0.79 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1154416 | 0.76 | — | — | |
| SCHEMBL378661 | 0.75 | FGFR1 (0.30) | — | |
| SCHEMBL13711464 | 0.73 | MAPT (0.57) | ALDH1A1L3MBTL1KDM4ENPC1MAPT | |
| SCHEMBL8908207 | 0.73 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL27510266 | 0.72 | HSP90AA1 (0.32) | — | |
| SCHEMBL8622721 | 0.72 | ADRB2 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL9951530 | 0.72 | CYP3A4 (0.37) | KDM4EMAPT | |
| SCHEMBL337778 | 0.71 | CA12 (0.41) | L3MBTL1KDM4EMAPTRAB9A | |
| SCHEMBL6268167 | 0.70 | COMT (0.35) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489655-B1 | Indolino-spiro-benzoxazine photochromic compounds and process for their preparation | ESSILOR INT (FR) | 1997-05-28 | — | — | EP | claimed |