Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 11/20 | 0.50 |
| ▸ | PPARD | Q03181 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642303 | 0.90 | PPARG (0.52) | LTA4HPPARAPPARDMAPK1PPARG | |
| SCHEMBL8907594 | 0.87 | LTA4H (0.51) | LTA4HPPARAPPARDPPARGRARB | |
| SCHEMBL8644115 | 0.80 | LTA4H (0.51) | LTA4H | |
| SCHEMBL7115531 | 0.78 | KDM4E (0.54) | LTA4HKDM4ESMN1; SMN2HTTFAAH | |
| SCHEMBL10877407 | 0.74 | LTA4H (0.52) | LTA4HPPARAPPARDKDM4ESMN1; SMN2 | |
| SCHEMBL7118378 | 0.74 | KDM4E (0.50) | LTA4HPPARAPPARDKDM4ESMN1; SMN2 | |
| SCHEMBL8641130 | 0.73 | LTA4H (0.56) | LTA4HPPARASMN1; SMN2PPARGHTT | |
| SCHEMBL13251237 | 0.72 | TDP1 (0.53) | KDM4ESMN1; SMN2MAPK1RARBHTT | |
| SCHEMBL6056484 | 0.72 | MAPK1 (0.43) | LTA4HPPARAPPARDKDM4ESMN1; SMN2 | |
| Bromide SCHEMBL6049707 | 0.71 | LTA4H (0.57) | LTA4HPPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | claimed |