Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642303 | 0.86 | PPARG (0.52) | LTA4H | |
| SCHEMBL8640498 | 0.86 | LTA4H (0.55) | LTA4H | |
| SCHEMBL8641130 | 0.85 | LTA4H (0.56) | LTA4H | |
| SCHEMBL8907594 | 0.83 | LTA4H (0.51) | LTA4H | |
| Bromide SCHEMBL6049771 | 0.82 | LTA4H (0.56) | LTA4HL3MBTL1 | |
| Bromide SCHEMBL6049769 | 0.82 | LTA4H (0.56) | LTA4HL3MBTL1 | |
| SCHEMBL8907826 | 0.80 | LTA4H (0.51) | LTA4H | |
| SCHEMBL8639357 | 0.80 | LTA4H (0.52) | LTA4HL3MBTL1 | |
| SCHEMBL4105743 | 0.80 | ITGB3 (0.57) | LTA4HL3MBTL1 | |
| SCHEMBL6049753 | 0.78 | LTA4H (0.54) | LTA4HL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | claimed |
| US-5723492-A | LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use | G.D. SEARLE & CO. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |