Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326435 | 1.00 | DGAT1 (0.33) | DGAT1CTSKMAOAMAOB | |
| SCHEMBL10614000 | 0.83 | DGAT1 (0.34) | DGAT1CTSKMAOAMAOB | |
| SCHEMBL10613987 | 0.83 | DGAT1 (0.34) | DGAT1CTSKMAOAMAOB | |
| SCHEMBL27925918 | 0.78 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL4529907 | 0.76 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25087377 | 0.76 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL741932 | 0.76 | DGAT1 (0.34) | DGAT1CTSKMAOAMAOB | |
| SCHEMBL10936589 | 0.76 | CTSK (0.35) | DGAT1CTSKMAOAMAOB | |
| SCHEMBL8188812 | 0.76 | CYP2C9 (0.31) | DGAT1 | |
| SCHEMBL27461003 | 0.74 | CTSK (0.30) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629152-A | SYNTHETIC POLYPEPTIDES WITH DOUBLE HELICAL STRUCTURE, BINDING TO DNA AND RNA STRANDS, CONTAIN AZETIDINE RING | ISIS PHARMACEUTICALS, INC. (US) | 1997-05-13 | — | — | US | disclosed |