Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14125895 | 0.82 | GABRA1 (0.42) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL8377 | 0.81 | GABRA1 (0.43) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL1515785 | 0.80 | ALDH1A1 (0.49) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL6631529 | 0.79 | GABRA1 (0.38) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL26999259 | 0.79 | TSHR (0.39) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL26999257 | 0.79 | ACP3 (0.41) | ALDH1A1GABRA1GABRB2HPGDTSHR | |
| SCHEMBL8549265 | 0.79 | GABRA1 (0.38) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL13649911 | 0.78 | SLC2A1 (0.46) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL11558512 | 0.78 | ACP3 (0.44) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL26999261 | 0.78 | GABRA1 (0.39) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |