Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CYCS | P99999 | 4/20 | 0.39 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908103 | 0.92 | CHEK2 (0.40) | PPARGPPARACHEK2CYCSTOP1 | |
| SCHEMBL8865576 | 0.87 | PDE3B (0.41) | PPARGPPARACHEK2CYCSTOP1 | |
| SCHEMBL19718153 | 0.81 | PPARG (0.52) | PPARGPPARACYCSHDAC3HDAC4 | |
| SCHEMBL29831314 | 0.81 | PPARG (0.52) | PPARGPPARACYCSHDAC3HDAC4 | |
| SCHEMBL8865532 | 0.79 | PDE3B (0.34) | PPARGPPARACHEK2DYRK3MAP4K4 | |
| SCHEMBL29831938 | 0.79 | PPARG (0.51) | PPARGPPARAHDAC3HDAC4HDAC1 | |
| SCHEMBL19718136 | 0.79 | PPARG (0.51) | PPARGPPARAHDAC3HDAC4HDAC1 | |
| SCHEMBL7614765 | 0.78 | FABP4 (0.53) | CYCSTOP1KDM4EALDH1A1 | |
| SCHEMBL8908441 | 0.78 | L3MBTL1 (0.50) | — | |
| SCHEMBL8909617 | 0.77 | FABP4 (0.52) | CYCSTOP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | claimed |