Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333890 | 1.00 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL12796611 | 0.84 | LOXL2 (0.53) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL14641227 | 0.80 | HTR1A (0.46) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL2816694 | 0.80 | LOXL2 (0.47) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL1147625 | 0.79 | LOXL2 (0.43) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL18548747 | 0.77 | TLR8 (0.44) | KDM4EMAPT | |
| SCHEMBL13601938 | 0.77 | HTR1A (0.43) | HTR1AADRA1DADRA1AADRA1BLOXL2 | |
| SCHEMBL25404797 | 0.75 | PIK3CA (0.45) | SLC22A12CYP1A2 | |
| SCHEMBL25402921 | 0.75 | ALK (0.44) | CYP3A4KDM4EACP1PRNPRXFP1 | |
| SCHEMBL1147520 | 0.75 | KDM4E (0.65) | SLC22A12CYP1A2CYP2C9KDM4EPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |