Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.57 |
| ▸ | HTR3A | P46098 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HK1 | P19367 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891209 | 0.75 | HTR3A (0.59) | HRH4HTR3AKDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL8901555 | 0.74 | ALDH1A1 (0.57) | HRH4HTR3AKDM4EALDH1A1GLA | |
| SCHEMBL11741104 | 0.74 | HRH4 (1.00) | HRH4HTR3AKDM4EALDH1A1GLA | |
| SCHEMBL30513776 | 0.74 | HRH4 (1.00) | HRH4HTR3AKDM4EALDH1A1GLA | |
| SCHEMBL30547000 | 0.74 | KDM4E (0.94) | HRH4HTR3AKDM4EALDH1A1GLA | |
| SCHEMBL742359 | 0.74 | KDM4E (0.94) | HRH4HTR3AKDM4EALDH1A1GLA | |
| SCHEMBL1083762 | 0.73 | RAB9A (0.77) | HRH4HTR3AKDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL11738196 | 0.73 | HRH4 (0.97) | HRH4HTR3AKDM4EALDH1A1GLA | |
| SCHEMBL3641196 | 0.72 | KDM4E (0.97) | HRH4HTR3AKDM4EALDH1A1GLA | |
| SCHEMBL8890608 | 0.71 | HTR3A (0.63) | HRH4HTR3AKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020820-A1 | HETEROARYL COMPOUNDS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |