Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907697 | 0.81 | DRD2 (0.42) | — | |
| SCHEMBL8908199 | 0.79 | DRD2 (0.42) | — | |
| SCHEMBL9825532 | 0.77 | LTA4H (0.45) | APP | |
| SCHEMBL8906800 | 0.77 | DRD2 (0.46) | — | |
| SCHEMBL8906856 | 0.75 | DRD2 (0.46) | — | |
| SCHEMBL9825281 | 0.73 | LTA4H (0.38) | — | |
| Water SCHEMBL9825376 | 0.73 | LTA4H (0.37) | — | |
| SCHEMBL8906794 | 0.72 | — | — | |
| SCHEMBL8906708 | 0.69 | DRD2 (0.32) | — | |
| SCHEMBL11828755 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620988-A | Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1997-04-15 | — | — | US | disclosed |
| US-5466698-A | Substituted tetrahydrophyridines and hydroxypiperidines as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1995-11-14 | — | — | US | disclosed |