Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8908423 | 0.99 | KDM4E (0.45) | KDM4EAPPFLT3NQO2HTT | |
| SCHEMBL8907203 | 0.93 | FLT3 (0.50) | KDM4EAPPFLT3HTTSLC2A1 | |
| SCHEMBL8899957 | 0.88 | APP (0.46) | KDM4EAPPFLT3HTTHTR1A | |
| SCHEMBL8907169 | 0.77 | APP (0.62) | APPFLT3KAT2BSLC2A1TOP2A | |
| SCHEMBL2585006 | 0.77 | PDE5A (0.60) | APPSLC2A1VCPMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11741441 | 0.76 | APP (0.60) | APPFLT3KAT2BSLC2A1TOP2A | |
| Hydrochloric Acid SCHEMBL8904749 | 0.76 | APP (0.60) | APPFLT3KAT2BSLC2A1TOP2A | |
| SCHEMBL8899767 | 0.76 | PRKCQ (0.42) | FLT3NQO2SLC2A1VCP | |
| SCHEMBL19003558 | 0.74 | KDM4E (0.48) | KDM4ENQO2ALDH1A1MEN1MAPT | |
| SCHEMBL9776841 | 0.74 | SLC2A1 (0.50) | KDM4EHTTSLC2A1ALDH1A1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |