Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 9/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908237 | 0.93 | KDM4E (0.46) | FLT3SLC2A1TOP2APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL8908423 | 0.92 | KDM4E (0.45) | FLT3SLC2A1TOP2APOLBKDM4E | |
| SCHEMBL8899957 | 0.83 | APP (0.46) | FLT3TOP2APOLBGAAKDM4E | |
| SCHEMBL8906085 | 0.78 | SLC2A1 (0.71) | FLT3SLC2A1TOP2APOLBGAA | |
| Hydrochloric Acid SCHEMBL8891454 | 0.77 | POLB (0.72) | FLT3SLC2A1TOP2APOLBGAA | |
| SCHEMBL8900938 | 0.77 | SLC2A1 (0.44) | FLT3SLC2A1TOP2APOLBGAA | |
| SCHEMBL2585006 | 0.75 | PDE5A (0.60) | SLC2A1APP | |
| SCHEMBL8900924 | 0.73 | VCP (0.46) | FLT3SLC2A1TOP2A | |
| SCHEMBL8907435 | 0.73 | SLC2A1 (0.44) | FLT3SLC2A1TOP2APOLBGAA | |
| SCHEMBL19003558 | 0.72 | KDM4E (0.48) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |