Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909742 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1HTTMEN1 | |
| SCHEMBL8909427 | 0.77 | HTT (0.50) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL4082665 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL3353890 | 0.71 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL5515200 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL10320769 | 0.70 | NPC1 (0.52) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL19548280 | 0.70 | HTT (0.53) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL18084992 | 0.70 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL13970898 | 0.70 | CYP3A4 (0.48) | ALDH1A1KDM4ETDP1HTTCYP3A4 | |
| SCHEMBL2187742 | 0.69 | ALDH1A1 (0.53) | ALDH1A1KDM4ETDP1HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670664-A | Photosensitive organic compounds that release carbon monoxide upon illumination | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 1997-09-23 | — | — | US | disclosed |