Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823178 | 0.84 | L3MBTL1 (0.47) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL14810055 | 0.79 | L3MBTL1 (0.48) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL8994708 | 0.78 | KMT2A (0.49) | L3MBTL1MEN1KMT2AHTTCA12 | |
| SCHEMBL9441174 | 0.76 | MEN1 (0.47) | L3MBTL1MEN1KMT2AHTTSRC | |
| SCHEMBL30523872 | 0.75 | L3MBTL1 (0.67) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL14810747 | 0.73 | MEN1 (0.47) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL9079781 | 0.72 | L3MBTL1 (0.41) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL30598260 | 0.71 | L3MBTL1 (0.55) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL3890511 | 0.71 | L3MBTL1 (0.55) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL22588410 | 0.71 | ALDH1A1 (0.57) | L3MBTL1LMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5600015-A | USING RUTHENIUM COMPLEX OF OPTICALLY ACTIVE ATROPISOMERIC DIPHOSPHINE LIGAND AS HYDROGENATION CATALYST | HOFFMANN-LA ROCHE INC. (US) | 1997-02-04 | — | — | US | disclosed |
| US-5302738-A | Chiral phosphines | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5274125-A | Chirale phosphines | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |