Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CTRC | Q99895 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908899 | 0.84 | TPMT (0.50) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL8909201 | 0.83 | KDM4E (0.42) | TSHRSMN1; SMN2RAB9AALDH1A1MAPK1 | |
| SCHEMBL16369792 | 0.80 | TSHR (0.48) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL9640394 | 0.80 | ACACB (0.38) | — | |
| SCHEMBL1425333 | 0.75 | KDM4E (0.46) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL1179149 | 0.74 | TPMT (0.56) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL1425060 | 0.74 | TPMT (0.48) | TPMTPIK3CAALOX15TSHRHIF1A | |
| SCHEMBL1424932 | 0.74 | TPMT (0.43) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL9069963 | 0.73 | KDM4E (0.49) | ALOX15TSHRHTTALDH1A1KDM5C | |
| Hydrochloric Acid SCHEMBL1425383 | 0.73 | KDM4E (0.45) | TPMTALOX15TSHRHIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601113-B1 | RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE | CIS BIO INT (FR) | 1997-01-08 | — | — | EP | disclosed |
| WO-1993005049-A1 | RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE | CIS BIO INTERNATIONAL (FR) | 1993-03-18 | — | — | WO | disclosed |