Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CTRC | Q99895 | 2/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179149 | 0.88 | TPMT (0.56) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11078337 | 0.86 | TPMT (0.54) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1179035 | 0.86 | TPMT (0.54) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL20346112 | 0.85 | CTRC (0.61) | SMN1; SMN2ALDH1A1CTRCHPGDKDM4E | |
| SCHEMBL8908305 | 0.84 | TPMT (0.37) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL16706636 | 0.83 | CTRC (0.66) | SMN1; SMN2ALDH1A1CTRCTDP1HPGD | |
| SCHEMBL21096025 | 0.83 | CYP3A4 (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL2085141 | 0.80 | TPMT (0.48) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL3686639 | 0.80 | ALOX15 (0.71) | TPMTALOX15TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL501900 | 0.78 | SMN1; SMN2 (0.55) | TPMTALOX15TSHRHIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601113-B1 | RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE | CIS BIO INT (FR) | 1997-01-08 | — | — | EP | disclosed |
| WO-1993005049-A1 | RARE EARTH MACROCYCLIC COMPLEXES AND USE THEREOF FOR REDUCTION OF DISTURBANCES IN AN ASSAY USING FLUORESCENCE | CIS BIO INTERNATIONAL (FR) | 1993-03-18 | — | — | WO | disclosed |