Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811051 | 0.82 | MT-CO2 (0.58) | MT-CO2KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL17481769 | 0.75 | MT-CO2 (0.51) | MT-CO2KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL8906567 | 0.75 | MAPK1 (0.66) | MT-CO2KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL486586 | 0.75 | ALDH1A1 (0.72) | MT-CO2KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL16539324 | 0.74 | MT-CO2 (0.50) | MT-CO2KMT2AMAPTKDM4EPOLB | |
| SCHEMBL16539777 | 0.73 | POLB (0.69) | MT-CO2KMT2AMAPTKDM4EHPGD | |
| SCHEMBL16321423 | 0.72 | MT-CO2 (0.48) | MT-CO2KMT2AMAPTPOLBMEN1 | |
| SCHEMBL7522548 | 0.72 | MT-CO2 (0.51) | MT-CO2KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL7520380 | 0.72 | MT-CO2 (0.51) | MT-CO2KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL8906911 | 0.71 | MT-CO2 (0.50) | MT-CO2KMT2AMAPTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616615-A | ANTICONVULSANTS | HOWARD UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |
| US-5468775-A | Anticonvulsants | HOWARD UNIVERSITY (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1993017678-A1 | ENAMINONE ESTERS | HOWARD UNIVERSITY (US) | 1993-09-16 | — | — | WO | disclosed |