Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545141 | 0.75 | ALDH1A1 (0.52) | MT-CO2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL29377973 | 0.75 | ALDH1A1 (0.52) | MT-CO2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL8908353 | 0.71 | MT-CO2 (0.83) | MT-CO2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL29958702 | 0.68 | F7 (0.40) | KMT2AMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL27033724 | 0.68 | F7 (0.40) | KMT2AMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3393144 | 0.67 | L3MBTL1 (0.47) | KMT2AMAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL13920758 | 0.66 | PSEN1 (0.32) | MAPTALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL23670494 | 0.65 | P2RX7 (0.46) | ALDH1A1AKR1C3 | |
| SCHEMBL5896818 | 0.65 | GPBAR1 (0.48) | — | |
| SCHEMBL29552779 | 0.65 | P2RX7 (0.46) | ALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616615-A | ANTICONVULSANTS | HOWARD UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |
| US-5468775-A | Anticonvulsants | HOWARD UNIVERSITY (US) | 1995-11-21 | — | — | US | disclosed |
| WO-1993017678-A1 | ENAMINONE ESTERS | HOWARD UNIVERSITY (US) | 1993-09-16 | — | — | WO | disclosed |