Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.40 |
| ▸ | KIF11 | P52732 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345505 | 0.77 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL15345785 | 0.73 | UGT2B7 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL15345403 | 0.70 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL15345447 | 0.68 | AOC3 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL3742635 | 0.66 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL808716 | 0.66 | KCNA5 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2KIF11 | |
| SCHEMBL808715 | 0.66 | KCNA5 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2KIF11 | |
| SCHEMBL8908377 | 0.66 | MC5R (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17023194 | 0.65 | SLC13A5 (0.53) | SLC6A4KIF11 | |
| SCHEMBL2768760 | 0.65 | KIF11 (0.42) | SLC6A4SLC6A3KCNH2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048676-A1 | TRIPHENYLALKYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |