Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 3/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | HRAS | P01112 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14353079 | 0.75 | HRAS (0.64) | MC5RMC4RMC3RHRASMAPK1 | |
| SCHEMBL17023194 | 0.75 | SLC13A5 (0.53) | KMT2ACYP1A2CYP2A6SLC6A4HTR2A | |
| SCHEMBL14353403 | 0.73 | CYP1A2 (0.55) | MC5RMC4RMC3RHRASMAPK1 | |
| SCHEMBL15059232 | 0.71 | CYP1A2 (0.50) | MC5RMC4RKMT2ACYP1A2CYP2A6 | |
| SCHEMBL10048276 | 0.70 | CYP1A2 (0.53) | MC5RMC4RMC3RMAPK1KMT2A | |
| SCHEMBL8381271 | 0.69 | ASIC3 (0.43) | MAPK1PPARG | |
| SCHEMBL6008141 | 0.66 | MC5R (0.71) | MC5RMC4RMC3RMAPK1KMT2A | |
| SCHEMBL28508798 | 0.66 | SLC13A5 (0.57) | CYP1A2CYP2A6SLC6A4HTR2A | |
| SCHEMBL28168169 | 0.66 | MC5R (0.51) | MC5RMC4RMC3RMAPK1KMT2A | |
| SCHEMBL8908374 | 0.66 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048676-A1 | TRIPHENYLALKYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |