SCHEMBL8908383

SCHEMBL8908383

CCN(CC)S(=O)(=O)c1cccc(S)c1S

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 6/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2C19 P33261 2/20 0.51
HIF1A Q16665 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 4/20 0.46
TSHR P16473 4/20 0.46
LMNA P02545 4/20 0.43
KDM4E B2RXH2 4/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
HPGD P15428 2/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9306878 0.73 HTT (0.53) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL9001236 0.72 ALDH1A1 (0.54) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL13979927 0.71 HTT (0.64) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL9307687 0.70 SMN1; SMN2 (0.55) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL7234935 0.70 HTT (0.50) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL5049419 0.70 L3MBTL1 (0.76) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL27729470 0.70 KMT2A (0.51) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL7233428 0.70 L3MBTL1 (0.53) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL7233134 0.70 GAA (0.52) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL7759472 0.69 HTT (0.49) HTTL3MBTL1CYP1A2CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9309886-A None JP disclosed
JP-H09309886-A SUBSTITUTED BENZENEDITHIOL METAL COMPLEX AND ITS PRODUCTION SUMITOMO SEIKA CHEM CO LTD 1997-12-02 JP disclosed