SCHEMBL7233134

SCHEMBL7233134

CCN(CC)S(=O)(=O)c1ccccc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.52
HTT P42858 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CYP2C9 P11712 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.47
LMNA P02545 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13395312 0.83 GAA (0.50) GAAHTTL3MBTL1CYP1A2CYP2C19
SCHEMBL12087004 0.82 HTT (0.49) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL10693402 0.82 TSHR (0.48) GAATDP1CA12CA1CA2
SCHEMBL7233428 0.81 L3MBTL1 (0.53) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL12576014 0.80 HTT (0.47) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL8172210 0.80 TAS2R14 (0.54) L3MBTL1ALDH1A1
SCHEMBL534224 0.79 LMNA (0.64) GAAL3MBTL1TDP1CA12CA1
SCHEMBL9001236 0.78 ALDH1A1 (0.54) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL17774582 0.78 LMNA (0.46) HTTL3MBTL1CYP1A2CYP2C19HIF1A
SCHEMBL20930300 0.78 GAA (0.48) GAAHTTCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2172461-A1 DI(ARYLAMINO)ARYL COMPOUND Astellas Pharma Inc. (JP) 2010-04-07 EP disclosed
US-6610853-B1 N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide KUREHA KAGAKU KOGYO K.K. (JP) 2003-08-26 US disclosed
EP-1069112-A1 N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-01-17 EP disclosed
EP-0303415-B1 Herbicidally active phenoxy-alkanecarboxylic acid derivatives SUNTORY LTD (JP) 1994-11-30 EP disclosed
US-5205855-A Postemergence, preemergence herbicides SUNTORY LIMITED (JP) 1993-04-27 US disclosed
US-4976773-A SELECTIVITY BETWEEN MONOCOYLEDON PLANTS SUNTORY LIMITED (JP) 1990-12-11 US disclosed
US-4760183-A Process for the preparation of aromatic dialkylamines HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0023140-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP disclosed
EP-0023141-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-11 EP disclosed
US-4424073-A N-(PYRIMIDINYLAMINOCARBONYL/SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-01-03 US disclosed
US-4417917-A BENZENE DISULFONIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-29 US disclosed
US-4372778-A Herbicidal N-(pyridinylaminocarbonyl)benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-08 US disclosed
EP-0070041-A2 Substituted benzenesulfonyl isocyanates and isothiocyanates and processes for their preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-19 EP disclosed
US-4342587-A Herbicidal pyridinsulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-08-03 US disclosed
US-4310346-A HERBICIDES AND PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-12 US disclosed
US-4293330-A Herbicidal N-(pyridinylaminocarbonyl)benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-06 US disclosed
EP-0023141-A2 Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-28 EP disclosed
EP-0023140-A2 Herbicidal sulfonamides, preparation and use thereof, and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-28 EP disclosed
US-4033943-A Fiber reactive water soluble 2,4,6-triamino, 3-cyano pyridine-(5) azo dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 US disclosed