Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinolin-4-Amine SCHEMBL27598920 | 1.00 | NCF1 (0.68) | NCF1HTTHSD17B10L3MBTL1CYP1A2 | |
| Quinolin-4-Amine SCHEMBL28216975 | 0.83 | NCF1 (0.78) | NCF1HTTHSD17B10CYP1A2LOXL2 | |
| Quinolin-4-Amine SCHEMBL278276 | 0.82 | NCF1 (1.00) | NCF1HTTHSD17B10LOXL2NR4A2 | |
| Quinolin-4-Amine SCHEMBL29493365 | 0.82 | NCF1 (1.00) | NCF1HTTHSD17B10LOXL2NR4A2 | |
| Quinolin-4-Amine SCHEMBL27902567 | 0.82 | NCF1 (0.70) | NCF1HTTHSD17B10CYP1A2LOXL2 | |
| Trifluoroacetic Acid SCHEMBL28146694 | 0.81 | L3MBTL1 (0.64) | NCF1L3MBTL1CYP1A2LOXL2SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL3567636 | 0.81 | NCF1 (0.42) | NCF1HTTHSD17B10L3MBTL1SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL28101328 | 0.81 | SMN1; SMN2 (0.44) | NCF1L3MBTL1CYP1A2SLC22A12PTPN11 | |
| Quinolin-4-Amine SCHEMBL4384971 | 0.80 | NCF1 (0.95) | NCF1HTTHSD17B10LOXL2NR4A2 | |
| Quinolin-4-Amine SCHEMBL5792741 | 0.80 | NCF1 (0.95) | NCF1HTTHSD17B10LOXL2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |