Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469518 | 0.85 | MTNR1A (0.50) | LTA4HCYP1A2CYP2C9CYP2C19MTNR1A | |
| SCHEMBL5684114 | 0.84 | LTA4H (0.65) | LTA4HPPARGPPARACALM1L3MBTL1 | |
| SCHEMBL29086619 | 0.81 | CYP1A2 (0.53) | PPARGPPARACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17807116 | 0.81 | LTA4H (0.61) | LTA4HPPARGPPARACALM1L3MBTL1 | |
| SCHEMBL8638375 | 0.78 | LTA4H (0.57) | LTA4HPPARGPPARACALM1L3MBTL1 | |
| SCHEMBL17710899 | 0.74 | CYP1A2 (0.67) | LTA4HPPARGPPARAL3MBTL1CYP1A2 | |
| SCHEMBL20863171 | 0.74 | LTA4H (0.52) | LTA4HPPARGPPARACALM1L3MBTL1 | |
| SCHEMBL17710847 | 0.74 | CYP1A2 (0.67) | LTA4HPPARGPPARAL3MBTL1CYP1A2 | |
| SCHEMBL8673825 | 0.73 | LTA4H (0.47) | LTA4HPPARGPPARACALM1L3MBTL1 | |
| SCHEMBL7140105 | 0.73 | LTA4H (0.97) | LTA4HCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | disclosed |