Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946004 | 0.82 | HSD11B1 (0.44) | HSD11B1CRHR1EGLN2MEN1KMT2A | |
| SCHEMBL8382134 | 0.77 | HSD11B1 (0.40) | HSD11B1CRHR1EGLN2MEN1KMT2A | |
| SCHEMBL31627478 | 0.77 | CYP17A1 (0.36) | DPP4 | |
| SCHEMBL10879071 | 0.75 | HSD11B1 (0.40) | HSD11B1CRHR1EGLN2NPC1DPP4 | |
| SCHEMBL9421338 | 0.75 | ESR1 (0.44) | KMT2AALPL | |
| SCHEMBL11338993 | 0.73 | HSD11B1 (0.37) | HSD11B1EGLN2NPC1DPP4TNKS | |
| SCHEMBL6528504 | 0.71 | HSD11B1 (0.51) | HSD11B1EGLN2MEN1KMT2ATNKS | |
| SCHEMBL11154782 | 0.71 | HSD11B1 (0.47) | HSD11B1EGLN2MEN1KMT2ANPC1 | |
| SCHEMBL3600930 | 0.70 | DPP4 (0.46) | HSD11B1CRHR1MARS1DPP4 | |
| SCHEMBL28196508 | 0.69 | ALPL (0.44) | HSD11B1CRHR1MEN1KMT2AMARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063234-B | Preparation method of sulconazole nitrate | 山东京卫制药有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-114409600-A | Synthetic method of enilconazole | 武汉回盛生物科技股份有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-104341350-B | A kind of process for purification of the ethanol of health azole drug parent nucleus (±) α (2,4 dichlorophenyl) 1H imidazoles 1 | 陕西汉江药业集团股份有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-119143677-A | Preparation method of fenticonazole or nitrate thereof | 浙江东亚药业股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-118079866-A | Preparation method of organic hybridization monolithic column and capillary electrophoresis method for separating chiral drugs by using organic hybridization monolithic column | 大连医科大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-116063234-B | Preparation method of sulconazole nitrate | 山东京卫制药有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116063234-A | Preparation method of sulconazole nitrate | 山东京卫制药有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115028586-A | Preparation method of chiral (S) -imazalil | 池州中瑞化工有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-114409600-A | Synthetic method of enilconazole | 武汉回盛生物科技股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114409600-A | Synthetic method of enilconazole | 武汉回盛生物科技股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| US-5591726-A | Heterocyclylalkyl diarylboron ester and thioester fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0703235-A2 | Heterocyclylalkyl diarylboron ester and thioester fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-03-27 | — | — | EP | disclosed |