Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15453213 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL5966208 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL38654646 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL349073 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL8688643 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL805503 | 0.75 | LOXL2 (0.64) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL11954971 | 0.74 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL31599195 | 0.72 | LOXL2 (0.67) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL334360 | 0.72 | LOXL2 (0.67) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL528996 | 0.72 | LOXL2 (0.60) | LOXL2NCF1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |